When Psy-Crow drinks a dangerously strong espresso, he becomes Hyper Psy-Crow. Jim must find a way to counteract the new threat before it cause serious problems for the universe.
Jim, having had enough of Peter's deadly tantrums, sets about finding away to cure his transformation problems. The quest leads us back to how and why Peter is so intelligent.
Psy-Crow forces the narrator to read that him and Professor Monkey-For-A-Head have overthrown Queen Slug-for-a-Butt, which automatically happens. Ethel Bleveridge takes her in. To stop them, Jim and Princess What's-Her-Name need her help.
Evil the Cat comes into possession of a key that allows him to control The Great Beast That Dares Not Speak Its Name. But his plans are put in jeopardy when the Beast turns out to be in Jim's possession.
Bob the Killer Goldfish invents a device that can transfer "evolution energy" from its target to its user. This devolves the target to a lower life form and takes Bob to a higher stage of evolution. Jim and Peter become its victims.
Jim must stop the invasion of cyber-furniture that turns anyone who sits on it into a zombie-like couch potato. Pete falls victim to a cyber-sofa, but the nerdy president of Jim's fan club jumps in to back Jim up.
Princess What's-Her-Name explains Jim how her rivalry with her evil sister Queen Slug-for-a-Butt began and decides that the time has finally come for her and Jim to overthrow her evil sister once and for all. She also tries to dance.
Jim needs to find a way to improve the show's ratings. He must also investigate the epidemic of people turning into apes after using cosmetic products.
Evil the Cat teams up with Malice the Dog, the love of his life. The villainous couple steals Jim's Hairpin of Destiny to summon The Fiend Which Dares Not Speak Its Name and destroy the universe and her Fleas of Eternal Slumber send Jim and his friends to the Realm of Nightmares.
Jim's hero status is threatened when he is apparently caught on camera committing various crimes. But is an incident with a photocopier really to blame?