Monogram pictures produced rather low budget films and cut costs in every way imaginable. Karloff made this entire film possible with his great acting as Dr. Adrian, dedicating his career to finding a cure for the dread disease Polio. He ties to help the only person in town who believes he can cure her from paralyzis. Karloff soon learns that he needs spinal fluid from a human being, he tries to blame the Ape for his horrors. This "APE Film" finished Karloff's contract with Monogram and he returned after eighteen(18)years when Monogram became Allied Artists in 1953 where he made "Frankenstein 1970".
