At the end of the movie, Vianne calls to have her family open the door instead of knocking. They explained that Vianne and their dad shared a phone. She then says she is there to pick up her phone (the one that rang) and her purse.
When Madea slaps Joe in the hospital waiting room, his false teeth fall out as they were supposed to, but the fake "gums" visibly almost fall out with them, requiring Tyler Perry to quickly close his mouth to keep them from falling out too.
When Heathrow calls Joe's phone, there are 2 mistakes.
1.) When Joe pulls out the phone, an iPhone slips out, and he quickly puts it back in.
2.) The phone Joe answers has an iPhone ringtone even though it's clearly an Android phone.
Vianne's children's ages are mentioned, but she states that Sylvia and AJ are 2 years apart in age, and Jesse is one year apart in age from AJ and 3 years apart from Sylvia.
It's revealed that Heathrow is the grandfather to Anthony and Vianne's children, but throughout the entire film they address him as Uncle Heathrow.