During the radio conversation between Pablo and Tata, Tata gives him an example of Nelson Mandela's Nobel prize: Mandela received the prize a week after death of Pablo Escobar.
Escobar died 2 Dec 93. Mendela received Nobel 10 Dec 93. The Peace Prize is awarded in October.
When Pablo goes out for a ride in his car, a black Toyota Corolla is seen in the background. That model came out in 2006.
The cafeteria that Pablo buys his ice cream from in Medellin has a large mural of the lower Manhattan skyline on the wall behind the cashier. The Twin Towers are nowhere to be seen and you can make out the lower floors of the new WTC1 next to the Global Financial Center.
When Mrs. Escobar puts a tea bag down on a napkin, it is a tea bag of the tetrahedron shape, which wasn't invented until 1997.