Alessa's lab number is B-09 S. This is a reference to her comic book alias, the Bride of Nine Spiders.
The character Scythe is the first supervillain that Iron Fist faced in the comics from his second appearance in Marvel Premiere.
This episode is directed by actor-musician RZA. RZA is a member of the hip-hop group Wu-Tang Clan and created many of their signature beats, which include samples from several legendary kung fu movies. RZA also wrote, directed and starred in the feature film The Man with the Iron Fists (2012). Coincidentally, Dave Bautista was also featured in that movie and would go on to star as Drax in Guardians of the Galaxy (2014) and its sequel, which is part of the Marvel Cinematic Universe that now includes the character Iron Fist.
This is the first appearance of Lei Kung.