The movie was actually filmed in Fresno, California because the budget did not allow for the original filming location of Cleveland, Ohio.
Natasha Lyonne and Clea DuVall previously worked together in But I'm a Cheerleader (1999), also directed by Jamie Babbit.
Fresno means "ash tree" in Spanish. One scene in the movie shows a place called Ash Tree.
Fresno is the fifth largest city in California.
Fresno is a city of 515,000 inhabitants and is the 34th largest city in the United States.