When Jack is seen entering CIA headquarters, he walks past two men having a conversation in the lobby. The man facing towards the camera is real-life CIA Director William J. Burns, who has been in the position since 2021.
When Ryan is reviewing Chavez's file the entry "Division: CIA-Rainbow" is shown on the computer screen. In the Jack Ryan novels Chavez was the Executive Officer (second in command) of Rainbow, a multinational counter-terrorist unit.
When Ryan and Chavez are discussing the former's past it's mentioned how Chavez was at the top of his BUD/S class making him a former SEAL. In the Jack Ryan novels Chavez was a Sergeant in the 7th Infantry Division.
Domingo Chavez's birthday is said to be January 12, 1976 making the character exactly one day older than Michael Peña, the actor who plays him.