Bebe Neuwirth and James Cromwell both appeared in this episode as well as in different Star Trek:TNG productions with the same title of "First Contact." Bebe Neuwirth portrayed Nurse Lanel in the ST:TNG S4:E15 "First Contact" (1991). James Cromwell appeared as Zefram Cochrane in "Star Trek First Contact" (1996). Further, Robert Joy appears in this episode and portrayed Yerid in Star Trek: Voyager S7E16 "Work Force II" (2001).