At 1:09:28, the meteor is going leftwards while other times, it's going rightwards.
The asteroid's high speed journey through the atmosphere would have only been seconds or a few minutes at most, so the fireball should only have appeared at the very end of the movie.
The asteroid, as viewed from the same neighborhood, kept changing its trajectory, which is impossible. Sometimes its downwards path was from left to right, other times it was from right to left.
On the bridge when Liza meets Nate the puppies in his arms change from left and right multiple times.
Nick Kroll's character has a button down shirt that alternates in some shots from having one button and two buttons closed.
If familiar with LA, the path walked by Liza and Young Liza makes no geographical sense. Most of the places they stop at or walk through are far apart from each other, in most cases in opposite directions, and would take hours to get to each by foot. Thereby, spending most of the day walking rather than accomplishing their goals.