In the second season of Mickey Mouse Funhouse, MacNeille was replaced by Debra Wilson as MacNeille was uninterested in continuing the series. Wilson, the first African-American performer of Daisy, also voiced the character in the holiday special Mickey Saves Christmas (2022).
This is the third Mickey Mouse television series to be aimed at preschoolers. The first being Mickey Mouse Clubhouse (2006) and the second being Mickey and the Roadster Racers (2017). Unlike the animation of those shows, this show has a mix of 2D and 3D backgrounds while the characters stay in 3D.