A distinctive visual motive is the patterns on the characters' clothing/skin staying the same. The patterns are developed as a full-screen image and then sent to the production house, where the characters are modified to fill the patterns in over the character skin/clothing. With this technique, when a character moves, their patterns do not follow but are displayed as a "static" background.
In the opening theme song, Shnitzel's part can actually be translated with closed captioning as "you share a big piece with everyone".
During the beginning credits, the dish in the oven is always different.
Panini originally had an outfit which only revealed her face (which was to have pointy ears), and was to bully Chowder in a manner similar to Rugrats (1991)'s Angelica Pickles. But C.H. Greenblatt disliked unctuous obnoxious characters like Angelica, so decided to make Panini cuter and sweeter: he made the pointy ears bunny ears, and made her have a crush on Chowder; since Chowder is not old enough for girls, Greenblatt felt this would make the romance much funnier.