- Lindsey Strauss: It was a comet, Luke. The boy saw a comet.
- Lucas Scott: Okay...
- Lindsey Strauss: The boy saw the comet and felt as though his life had meaning. And when it went away, he waited his entire life for it to come back to him.
- Lucas Scott: Lindsey I love you, but this isn't the time for a book review okay?
- Lindsey Strauss: What was the first day you ever talked to Peyton?
- Lucas Scott: Lindsey...
- Lindsey Strauss: Please.
- Lucas Scott: Her car broke down.
- Lindsey Strauss: The boy saw the comet and suddenly his life had meaning. I'm sorry Lucas, I can't marry you.
- Skills Taylor: Wait! Maybe Lucas will say the wrong name on the alter just like Ross did on Friends.
- Skills Taylor: [referring to Peyton] Baby girl you are so far from ok man you ain't even in the same area code.
- Karen Roe: I... I know we have to go, but there really is something I wanted to tell you... both of you. You know, in life, if you let it, you can always come up with reasons to give up. But if you don't, you might just find love in places you never imagined... in a new relationship or in your work...
- Brooke Davis: Or in your children.
- Karen Roe: Whatever it is, just don't give up on it. And if you don't get it, well, you might get something better.
- Skills Taylor: How about this? I say we drug Lindsey first, even though I love her. Then we throw you in the wedding gown, so when Lucas lifts up the veil. BAM! It's on.
- TV character Bugs Bunny: [Jamie watching TV in the motel, after being kidnapped by Nanny Carrie] Run for your lives. She is a witch.
- Nathan Scott: Jamie is gonna be the man. I'm gonna be second best. You'll be lucky to make the top 10, Luke.
- Lucas Scott: Thanks.
- Lily Roe Scott: That's what you have to call me.
- James Scott: I do not.
- Lily Roe Scott: You do so. Say it. Aunt Lily.
- Cop 1: What the hell are you doing?
- Nathan Scott: My son is missing.
- Cop 1: Right calm down you could've got yourself killed!
- Nathan Scott: We just left the wedding okay, all the guests are gone and my son missing. He's 4 and a half years old.
- Cop 2: Have you been drinking sir? Maybe been to the reception?
- Nathan Scott: What kind of question is that 'Have I been drinking?'
- Cop 2: You need to listen to me...
- Nathan Scott: No you listen to me! My name is Nathan Scott okay, my father is Dan Scott, he was arrested for murder okay he's a bad guy and he was here today. Now either one of you two idiots gets on your radio right now and finds my son or I'll knock you both out and I'll do it myself!
- Cop 1: Hey, you needa relax. Alright.