Gretchen mentions to Sucre with some amusement that his name means sugar, which he confirms. A viewer not otherwise aware might conclude that the language in question is Fernando's native/near-native tongue of Spanish, but this is not actually the case. Sucre means sugar in French (the Spanish word for sugar is "azúcar"); the only real meaning for "sucre" in Spanish is the former national currency of Ecuador.
This episode marks the first time that Michael Scofield had arranged the death of another character thus making this his first kill.