- The Lizard releases all reptiles in Central Park Zoo and goes on a rampage. Spider-Man saves everybody, but the Lizard uses a gorilla to distract Spider-Man so he can make his getaway. The Lizard derails two subway cars to make a breeding ground for his reptile army. The Lizard then decides to turn New York into a massive jungle to perfect his reptile army, and Spider-Man must stop him.
- All of the reptiles in Central Park Zoo are released by the Lizard, to cause chaos and confusion. Spider-Man is able to save all of the people trapped by the escaped reptiles, but an encounter with a gorilla let loose by the Lizard leaves Spidey unable to notice the Lizard stealing all the zoos' reptiles. In his underground lair, the Lizard derails two subway cars, creating an impenetrable breeding ground in-between them in the subway tunnel. In the meantime, Spidey attempts to rid himself of a troublesome cold that has begun to affect him. Spidey finds out about the Lizards' subway plans , but is unable to stop him from sealing off part of the subway tunnel. Eventually, he digs his way into the sealed breeding ground, but is overrun by the amassed reptiles and the Lizard escapes. With time to spare, Spidey heads for the nearest doctor to try and solve his current sneezing problem. The Lizard then completes his master plan by activating a weather control device, turning New York into a humid jungle, and then releasing his army of reptiles. A still-suffering Spidey then faces the Lizard and his reptiles, and attempts to return the city to normal.—Mark Fair
- A massive breakout at the zoo captures the attention of Spider-Man. He intervenes and returns most of the animals to their cages, excluding the reptiles. Unknown to him, this event has been orchestrated by The Lizard. His latest plan is to turn all of New York into a jungle and overrun it with reptiles, controlled by him of course.
Spider-Man soon discovers the Lizard's involvement and attempts to stop him. Unfortunately Spider-Man succumbs to a sneezing fit which allows the Lizard to escape.
The Lizard eventually floods the city with a weather-altering device, providing a large playground for his reptile army.
After he is goal is realized, Spider-Man is able to neutralize the Lizard's ability to control the reptiles and returns them all to their cages. Lizard included.
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