Bailey reveals that Burke's middle name is Xavier.
Every episode of the show is named after a famous song. "Deterioration of Flight or Flight Response" is a song by The Flaming Lips.
Denny and Adele share a scene in season 1 of Supernatural (2005).
Both Tiffany Hines and Hallee Hirsch, who guest star in this episode as Webber's niece's friends, played daughters of doctors in TV series. Tiffany as Michelle, Cam Saroyan's daughter in Bones (Cam was the coroner for Jeffersonian) and Hallee as Rachel Greene, Mark Greene's daughter in ER (from the eighth season until the fifteenth)
Tessa Thompson and Charles Duckworth both were in Veronica Mars.