According to Tom Ruegger, the character of Neivel Nosenest got him name from the title of An American Tail: Fievel Goes West (1991).
Last episode of the series.
When the conductor Nosenest explains that the regular conductor Richard Stone is off on "a long deserved rest" he adds "in Carmarillo" as an aside. Carmarillo is home to Carmarillo State Mental Hospital.