Megan Mullally took 8 takes to successfully say her speech during this episode. Even after she wrote it down and stuck it on the wall next to her, and just below the bars. At one point, Debra Messing decided to stick it on her face, so Megan could see it. If you watch carefully you can still see the part when she looks at the script because she can't remember it.
On the blackboard in Grace's office there is a list of her design clients; one of the names listed there is "Sandoval". Steve Sandoval is the associate producer of the show.
The gym that Will and Jack go to, Crunch Fitness, is an actual chain of gyms.