Spider-Man has been refusing to work with Black Cat because he doesn't want anyone close to him getting hurt anymore. Meanwhile, Kraven returns to New York to hunt down the Stalker, a creature he has been said to have created.
Spider-Man refuses to work with Black Cat, due to him losing Mary Jane in limbo during his last fight with the Green Goblin. Kraven soon resurfaces after taking the serum so he can track down his lover, Mariah after she has been transformed into a feral creature. Spider-Man must put aside his anger and guilt, in order to save his friend Mariah Crawford.—dawsonpersi