When Scott says Drew is "going all Shatner on them" he is referring to Drew talking slowly and dramatically right before, similar to how William Shatner played Kirk on Star Trek: The Original Series.
This is Bill Cobbs' first Appearance as Drew's Bus Driver, Tony.
This is the last episode to credit Kate Walsh as Nikki but she is never seen leaving the house. Meaning she could even still be in the house.
The title of this episode is a play on the movie title Eyes Wide Shut.
Mr. wick Becomes a Janitor at winfred Lauder.