Continuity: In the RV, the face of Cooker's beer can changes direction between shots.
Continuity: Junior has his eyelids tattooed. We never see the tattoos again.
Continuity: In one scene, Peter Gaulke takes a bong hit and clears the bong. In the next shot, the bong is filled with smoke.
Revealing mistakes: When Peter and Fred's teeth are knocked out on the hood of the Hispanic man's car, Fred's mustache falls off.
Errors in geography: Right after the crew discovers the camp where their competitors were killed by pygmies, they walk past a lake, supposedly in Ecuador. A mallard duck is swimming around behind them. Mallards don't live in South America.