Jane Fonda joined the film after the filming of Elizabethtown (2005) was pushed back a few months.
Shari Wacks designed the jewelry for the film.
When Viola asks Tanya Murphy what her favorite movies are, among the movies she names is Legally Blonde (2001). Robert Luketic, who directed this film, also directed Legally Blonde (2001).
Mark Ruffalo was originally offered the male lead, but declined.
All of the photos of Viola Fields on her table with famous people are real pictures of Jane Fonda with Oprah Winfrey, Ted Turner, Jon Voight and Gloria Steinem. The only "doctored" item is the cover of Time Magazine, which Fonda was set to appear on the cover of, however the Pope's Death in 2005 took the headline and subsequently, the cover.
Jennifer Lopez and Michael Vartan's last exes were Ben Affleck and Jennifer Garner, who married each other after breaking up with them.
The mansion where Charlie picks up the dogs she walks was used as the exterior of the Governor's mansion in the sitcom "Benson" (1979).