- Each console of the generation of 2001-2005 has a version of SC-II with one exclusive character in each version. The PS2 version has Heihachi Mishima, a character from the Tekken series. The Xbox version has the comic book character Spawn. The Gamecube version has Link from Nintendo's Zelda series.
- The Japanese version does not feature the extra characters Lizardman, Berserker and Assasin. If you unlock then during Weapon Master mode, you can use then on Versus mode.
- Along with the inclusion of exclusive characters in each of the different console versions, there are also other, minor differences in relation to these characters, such as the contents of the portrait artwork in the unlockable gallery.
- The arcade version, which predated the release of the console versions, does not include the characters Seung Mina, Sophitia, Lizardman, Berserker, Assassin, Necrid or the console specific characters Link, Heihachi and Spawn. The arcade version also used different cinematics for its opening and ending, which can be viewed as extra content in the console version galleries.
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