Terry Farrell reprises her role as Jadzia Dax, 2 years after her character was killed off at the end of the 6th season of "Star Trek: Deep Space Nine" in Tears of the Prophets (#6.26). This was Terry Farrell's last association with "Star Trek" before her retirement from acting in 2003.
Avery Brooks, who played Commander Benjaiman Sisko in the DS9 television series, did not provide the voice of his character in the video game. Kevin Michael Richardson provided the voice of Commander Sisko instead.
Michael Gough provided the voice of Chief Miles O'Brien. Chief Miles O'Brien was played in the DS9 TV series by Colm Meaney.
The game takes place in 2374.
The game loosely ties-in to the Star Trek: Deep Space Nine: Millennium novel trilogy (the three books in the miniseries:
Book I Of III The Fall Of Terok Nor, Book II Of III The War Of The Prophets, and Book III Of III Inferno).