- Continuity: Jerome rips his jacket sleeve seam while punching out the police officer, yet soon after it is intact.
- Crew or equipment visible: As Vincent gets ready for his first day at work as Jerome, he pulls out his shirt from the closet and you can see fingers of someone holding the closet door open.
- Continuity: In the scene at the piano recital, there's a bouquet of flowers to the right of the piano (shot from overhead), but when the pianist is finished, and takes a bow, the vase (and flowers) have vanished.
- Crew or equipment visible: The dolly track can be seen on the left of the screen when Vincent is standing in line to have a blood test done.
- Continuity: When the two men are swimming at night, they are sometimes shown to be naked, and other times (underwater shots) shown to be wearing boxers or swimming trunks.
- Crew or equipment visible: When the detective shows the picture of Vincent to the director, the power cable to his "hand-held display" (prop) is clearly visible running around his hand and up his sleeve.
- Audio/visual unsynchronized: Because they are occurring some distance away, the numerous rocket launches shown should not be audible until a several seconds after liftoff.
- Continuity: When Jerome and Eugene are out at the club, on the table there is smoke coming out of Jerome's wine glass before he blows the smoke into it.
- Continuity: After Irene and Vincent have sex, you can see that the bedroom walls are pure glass (including the corner of the house). You can also see a view of the beach and ocean. Later when Vincent is on the beach scrubbing himself with sand, the house is viewed from the beach. At that point you can see pillars in between pieces of glass on the house, including the corner.
- Factual errors: Using hair/eyelashes for genetic testing will fail if no follicle is attached, but this method is used when no other material is available or the information is being obtained surreptitiously (as Irene and the investigators are doing when they use this method). Urine is not the most efficient way to perform genetic testing when other samples are readily available, but the urine test was also performed to look for drug use as evidenced by Eugene's sample failing when he was drunk.
- Factual errors: When Vincent is confessing to Irene, he tells her he doesn't have 20 or 30 years, his heart is already 10,000 beats overdue. In an average male this would only be about 2 1/2 hours, not several years as the story suggests.
- Incorrectly regarded as goofs: In the beginning when Vincent is putting the blood into the fake thumb he puts it on his left thumb but he always uses his right hand to get tested. This is because Vincent himself is left-handed, but Jerome is right-handed so he had to make the switch when he assumed Jerome's life.
- Continuity: When Vincent alias Jerome has his interview at Gattaca you can see that the machine clearly shows a GNQ of 9.8612. When Irene gives the hair sample away for analysing, the woman at the counter states "9.3, quite a catch".
- Plot holes: Vincent dyes his hair to look more like Jerome: wouldn't that be very easy to spot under a microscope?
- Continuity: When Vincent is about to go in for his interview he grabs a bag of urine labeled 4/22 (most likely the date the urine was passed), later on there is a shot of the bags of urine hanging and one is clearly labeled 4/22 as well.
>>> WARNING: Here Be Spoilers <<<
Goofs below here contain information that may give away important plot points. You may not want to read any further if you've not already seen this title.
- Revealing mistakes: SPOILER: In the final scene when the real Jerome shuts himself in the incinerator, there should not be a way to turn on the machine from the inside. That seems to be a flaw in the design of such a machine; much the same as one would not put the on/off button to a blender inside the blender.
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