| Patrick McGoohan | ... | Number Six | |
| Virginia Maskell | ... | The Woman | |
| Guy Doleman | ... | Number Two | |
| Paul Eddington | ... | Cobb | |
| George Baker | ... | The New Number Two | |
| Angelo Muscat | ... | The Butler | |
| Barbara Yu Ling | ... | Taxi Driver | |
| Stephanie Randall | ... | Maid | |
| Jack Allen | ... | Doctor | |
| Fabia Drake | ... | Welfare Worker | |
| Denis Shaw | ... | Shopkeeper | |
| Oliver MacGreevy | ... | Gardener / Electrician | |
| Frederick Piper | ... | Ex-Admiral | |
| Patsy Smart | ... | Waitress | |
| Christopher Benjamin | ... | Labour Exchange Manager | |
| Peter Swanwick | ... | Supervisor | |
| David Garfield | ... | Hospital Attendant | |
| Peter Brace | ... | 1st Guardian | |
| Keith Peacock | ... | 2nd Guardian | |
| Fenella Fielding | ... | Loudspeaker Announcer (voice) (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Leo McKern | ... | Number Two | |
| Nadia Gray | ... | Nadia | |
| Finlay Currie | ... | General | |
| Richard Wattis | ... | Fotheringay | |
| Angelo Muscat | ... | The Butler | |
| Kevin Stoney | ... | Colonel J. | |
| Christopher Benjamin | ... | Number Two's Assistant | |
| David Arlen | ... | Karel | |
| Peter Swanwick | ... | Supervisor | |
| Hilda Barry | ... | No. 38 | |
| Jack Le White | ... | First Judge (as Jack Le-White) | |
| John Maxim | ... | Second Judge | |
| Lucy Griffiths | ... | Third Judge | |
| Fenella Fielding | ... | Loudspeaker Announcer (voice) (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) | |
| Frederick Piper | ... | Ex-Admiral (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Katherine Kath | ... | Engadine | |
| Sheila Allen | ... | Number Fourteen | |
| Colin Gordon | ... | Number Two | |
| Peter Bowles | ... | 'A' | |
| Angelo Muscat | ... | The Butler | |
| Georgina Cookson | ... | Blonde Lady | |
| Annette Carell | ... | 'B' (as Annette Carrell) | |
| Lucille Soong | ... | Flower Girl | |
| Bettina Le Beau | ... | Maid at Party (as Bettine Le Beau) | |
| Terry Yorke | ... | Thug | |
| Peter Brayham | ... | Thug | |
| Bill Cummings | ... | Henchman | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Eric Portman | ... | Number Two | |
| Rachel Herbert | ... | Number Fifty Eight | |
| George Benson | ... | Labour Exchange Manager | |
| Angelo Muscat | ... | The Butler | |
| Harold Berens | ... | Reporter | |
| John Cazabon | ... | Man in Cave | |
| Dene Cooper | ... | Photographer | |
| Kenneth Benda | ... | Supervisor | |
| Holly Doone | ... | Waitress | |
| Peter Brace | ... | 1st Mechanic | |
| Alf Joint | ... | 2nd Mechanic | |
| Fenella Fielding | ... | Loudspeaker Announcer (voice) (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six / Number Twelve | |
| Jane Merrow | ... | Alison | |
| Anton Rodgers | ... | Number Two | |
| Angelo Muscat | ... | The Butler | |
| Earl Cameron | ... | Supervisor | |
| Gay Cameron | ... | Number Thirty-Six | |
| David Nettheim | ... | Doctor | |
| Pat Keen | ... | Nurse | |
| Gerry Crampton | ... | 1st Guardian | |
| Dinny Powell | ... | 2nd Guardian (as Dinney Powell) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Colin Gordon | ... | Number Two | |
| John Castle | ... | Number Twelve | |
| Peter Howell | ... | Professor | |
| Angelo Muscat | ... | The Butler | |
| Al Mancini | ... | Announcer | |
| Betty McDowall | ... | Professor's Wife | |
| Peter Swanwick | ... | Supervisor | |
| Conrad Phillips | ... | Doctor | |
| Michael Miller | ... | Man in Buggy | |
| Keith Pyott | ... | Waiter | |
| Ian Fleming | ... | Man at Cafe and First Top Hat | |
| Norman Mitchell | ... | Mechanic | |
| Peter Bourne | ... | Projection Operator | |
| George Leech | ... | First Corridor Guard | |
| Jack Cooper | ... | Second Corridor Guard (as Jackie Cooper) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) | |
| Robert Rietty | ... | (voice) (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Donald Sinden | ... | The Colonel | |
| Patrick Cargill | ... | Thorpe | |
| Georgina Cookson | ... | Mrs. Butterworth | |
| Brian Worth | ... | Group Captain | |
| Richard Caldicot | ... | Commander | |
| Dennis Chinnery | ... | Gunther | |
| Jon Laurimore | ... | Ernst | |
| Nike Arrighi | ... | Gypsy Girl | |
| Grace Arnold | ... | Maid | |
| Larry Taylor | ... | Gypsy Man | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) | |
| Robert Rietty | ... | Number Two (voice) (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Mary Morris | ... | Number Two | |
| Duncan Macrae | ... | Doctor (as Duncan MacRae) | |
| Norma West | ... | Girl Bo-Peep | |
| Angelo Muscat | ... | The Butler | |
| Aubrey Morris | ... | Town Crier | |
| Bee Duffell | ... | Psychiatrist | |
| Camilla Hasse | ... | Day Supervisor | |
| Alan White | ... | Dutton | |
| Michael Nightingale | ... | Night Supervisor | |
| Patsy Smart | ... | Night Maid | |
| Denise Buckley | ... | Maid | |
| George Merritt | ... | Postman | |
| John Frawley | ... | Flowerman | |
| Lucy Griffiths | ... | Lady in Corridor | |
| William Lyon Brown | ... | 2nd Doctor | |
| Fenella Fielding | ... | Loudspeaker Announcer (voice) (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Ronald Radd | ... | Rook | |
| Patricia Jessel | ... | 1st Psychiatrist | |
| Peter Wyngarde | ... | Number Two | |
| Rosalie Crutchley | ... | Queen | |
| George Coulouris | ... | Man with the Stick | |
| Angelo Muscat | ... | The Butler | |
| Bee Duffell | ... | 2nd Psychiatrist | |
| Basil Dignam | ... | Supervisor | |
| Michael Danvers-Walker | ... | Painter (as Danvers Walker) | |
| Denis Shaw | ... | Shopkeeper | |
| Victor Platt | ... | Assistant Supervisor | |
| Shivaun O'Casey | ... | Nurse | |
| Geoffrey Reed | ... | Skipper | |
| Terence Donovan | ... | Sailor | |
| Joe Dunne | ... | 1st Tower Guard | |
| Romo Gorrara | ... | 2nd Tower Guard | |
| Fenella Fielding | ... | Loudspeaker Announcer (voice) (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Patrick Cargill | ... | Number Two | |
| Victor Maddern | ... | Bandmaster | |
| Basil Hoskins | ... | Number Fourteen | |
| Norman Scace | ... | Psychiatric Director | |
| Derek Aylward | ... | New Supervisor | |
| Angelo Muscat | ... | The Butler | |
| Hilary Heath | ... | Number Seventy-Three (as Hilary Dwyer) | |
| Arthur Gross | ... | Control Room Operator | |
| Peter Swanwick | ... | Supervisor | |
| Victor Woolf | ... | Shop Assistant | |
| Michael Segal | ... | Laboratory Technician | |
| Margo Andrew | ... | Shop Kiosk Girl | |
| Susan Sheers | ... | Female Code Expert | |
| Jack Cooper | ... | 1st Guardian (as Jackie Cooper) | |
| Fred Haggerty | ... | 2nd Guardian | |
| Eddie Powell | ... | 3rd Guardian | |
| George Leech | ... | 4th Guardian (as George Leach) | |
| Pat Gorman | ... | Hospital Orderly (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Derren Nesbitt | ... | New Number Two | |
| Annette Andre | ... | Watchmaker's Daughter | |
| Mark Eden | ... | Number One Hundred | |
| Andre Van Gyseghem | ... | Retiring Number Two | |
| Martin Miller | ... | Watchmaker / Number Fifty Four | |
| Wanda Ventham | ... | Computer Attendant | |
| Angelo Muscat | ... | The Butler | |
| Mark Burns | ... | Number Two's Assistant | |
| Peter Swanwick | ... | Supervisor | |
| Charles Lloyd Pack | ... | Artist | |
| Grace Arnold | ... | Number Thirty Six | |
| Arthur White | ... | Stall Holder | |
| Michael Bilton | ... | M.C. Councillor | |
| Gerry Crampton | ... | Kosho Game Opponent | |
| Fenella Fielding | ... | Loudspeaker Announcer (voice) (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Angela Browne | ... | Number Eighty-Six | |
| John Sharp | ... | Number Two (as John Sharpe) | |
| Angelo Muscat | ... | The Butler | |
| George Pravda | ... | Doctor | |
| Kathleen Breck | ... | Number Forty-Two | |
| Peter Swanwick | ... | Supervisor | |
| Thomas Heathcote | ... | Lobo Man | |
| Bartlett Mullins | ... | Committee Chairman | |
| Michael Miller | ... | Number Ninety-Three | |
| Joseph Cuby | ... | 1st Member of Social Group | |
| Michael Chow | ... | 2nd Member of Social Group | |
| June Ellis | ... | Number Forty-Eight | |
| John Hamblin | ... | 1st Woodland Man | |
| Michael Billington | ... | 2nd Woodland Man | |
| Fenella Fielding | ... | Loudspeaker Announcer (voice) (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Zena Walker | ... | Janet | |
| Clifford Evans | ... | Number Two | |
| Nigel Stock | ... | The Colonel / Number Six / Seltzman | |
| Angelo Muscat | ... | The Butler | |
| Hugo Schuster | ... | Seltzman / The Colonel | |
| John Wentworth | ... | Sir Charles | |
| James Bree | ... | Villiers | |
| Lloyd Lamble | ... | Stapleton | |
| Patrick Jordan | ... | Danvers | |
| Lockwood West | ... | Camera Shop Manager | |
| Fredric Abbott | ... | Potter | |
| Gertan Klauber | ... | Cafe Waiter | |
| Henry B. Longhurst | ... | Old Guest (as Henry Longhurst) | |
| Michael Danvers-Walker | ... | First New Man (as Danvers Walker) | |
| John Nolan | ... | Young Guest | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Alexis Kanner | ... | The Kid | |
| David Bauer | ... | The Judge / Number Two | |
| Valerie French | ... | Kathy | |
| Gordon Tanner | ... | Town Elder | |
| Gordon Sterne | ... | Bystander | |
| Michael Balfour | ... | Will | |
| Larry Taylor | ... | Mexican Sam | |
| Monti DeLyle | ... | Town Dignitary (as Monti De Lyle) | |
| Douglas Jones | ... | Horse Dealer | |
| Bill Nick | ... | First Gunman | |
| Leslie Crawford | ... | Second Gunman (as Les Crawford) | |
| Frank Maher | ... | Third Gunman | |
| Max Faulkner | ... | First Horseman | |
| Bill Cummings | ... | Second Horseman | |
| Eddie Eddon | ... | Third Horseman |
| Patrick McGoohan | ... | Number Six | |
| Kenneth Griffith | ... | Schnipps / Number Two | |
| Justine Lord | ... | Sonia | |
| Christopher Benjamin | ... | Potter | |
| Michael Brennan | ... | Killer Karminski | |
| Harold Berens | ... | Boxing M.C. | |
| Sheena Marshe | ... | Barmaid (as Sheena Marsh) | |
| Max Faulkner | ... | Scots Napoleon | |
| John Rees | ... | Welsh Napoleon | |
| Joe Gladwin | ... | Irish Napoleon | |
| John Drake | ... | Bowler | |
| Gaynor Steward | ... | Little Girl | |
| Graham Steward | ... | First Little Boy | |
| Stephen Howe | ... | Second Little Boy | |
| Alexis Kanner | ... | Photographer / Chief's voice (uncredited) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
| Patrick McGoohan | ... | Number Six | |
| Leo McKern | ... | Number Two | |
| Angelo Muscat | ... | The Butler | |
| Peter Swanwick | ... | Supervisor | |
| John Cazabon | ... | Umbrella Man | |
| John Maxim | ... | Number Eighty Six (scenes deleted) | |
| George Markstein | ... | Man behind desk in title sequence (uncredited) |
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