All of the sisters (June Allyson, Margaret O'Brien, Dame Elizabeth Taylor, and Janet Leigh) reportedly got along terrifically, like a real sorority. Allyson, who was several years older than most of her co-stars, managed to relate to the younger women and form strong bonds with them.
In addition to being pregnant with her first biological child, June Allyson also adopted her first child while this movie was in production. After Allyson learned that her daughter, Pamela Powell, had arrived for the first time at her home, she immediately left the set without asking permission, and raced home to hold her daughter. She returned later that day and told the rest of the cast and crew the joyous news.
Mr. Davis, the school teacher who could not bring himself to punish Amy, was portrayed by the same actor, Olin Howland, in Little Women (1933) and this movie, apparently in the same outfit. In both movies, he holds up Amy's slate with the same writing and cartoon drawing of the teacher, with a huge nose, with cartoon balloon stating, "YOUNG LADIES MY EYES ARE UPON YOU".
The basket that Margaret O'Brien carries around in this movie is the same basket that her Meet Me in St. Louis (1944) co-star Judy Garland carried in The Wizard of Oz (1939). The Wizard of Oz (1939) and this movie were produced by Mervyn LeRoy.
Mary Astor, who played the mother, Marmee, was only eleven years older than June Allyson. However, being born in 1906, she was clearly old enough to play the mother of a fifteen-year-old character.