35 wins & 81 nominations
- 2022 Nominee Brit
- Best Group
- 2022 Nominee Brit
- International Song of the Year
For "Heartbreak Anthem"Shared with: Galantis · David Guetta - 2021 Winner Brit
- British Group
Little Mix made history by becoming the first girl group to win this award. - 2019 Nominee Brit
- British Group
- 2017 Winner Blimp Award
- Favourite Global Music Star
- 2016 Nominee Blimp Award
- UK Favorite Music Act
- 2015 Nominee Blimp Award
- UK Favorite Music Act
- 2019 Nominee Teen Choice Award
- Choice International Artist
- 2019 Nominee Teen Choice Award
- Choice Summer Music Star: Group
- 2017 Nominee Teen Choice Award
- Choice Music: Group
- 2017 Nominee Teen Choice Award
- Choice Summer Music Star: Group
- 2013 Nominee Nickelodeon Kid's Choice Award
- Favourite UK Band
- 2012 Nominee Nickelodeon Kid's Choice Award
- Favourite UK Band
- 2012 Nominee Nickelodeon Kid's Choice Award
- Favourite UK Newcomer
- 2022 Nominee iHeartRadio Music Award
- Dance Song of the Year
For "Heartbreak Anthem"Shared with: Galantis · David Guetta
- 2016 Nominee Shorty Award
- Best Musician in Social Media
- 2015 Nominee Shorty Award
- Best Band
- 2014 Nominee Shorty Award
- Best UK
- 2020 Nominee VMA
- Best Group
- 2020 Winner Bravo Otto Germany
- Best Group (Beat-Gruppen)
- 2019 Winner Bravo Otto Germany
- Best Group (Beat-Gruppen)
- 2018 Nominee Bravo Otto Germany
- Best Group (Beat-Gruppen)
- 2013 Winner Bravo Otto Germany
- Newcomer of the Year - Newcomer des Jahres
- 2021 Nominee MTV Europe Music Award
- Best Group
- 2021 Winner MTV Europe Music Award - Regional
- Best UK & Ireland Act
Little Mix holds the record for most nominations and wins in this category. - 2020 Nominee MTV Europe Music Award
- Best Group
- 2020 Winner MTV Europe Music Award - Regional
- Best UK & Ireland Act
- 2019 Nominee British LGBT Award
- Celebrity Ally
- 2019 Winner British LGBT Award
- Change Makers
- 2021 Nominee Series Em Cena Award
- Best Music Group/Duo (Melhor Grupo/Duo Musical)
- 2018 Nominee Billboard Latin Music Award
- Crossover Artist of the Year
- 2014 Winner Japan Gold Disc Award
- New Artist of the Year - Western
- 2019 Winner Teen Award
- Best Group
- 2018 Winner Teen Award
- Best British Group
- 2017 Winner Teen Award
- Best British Group
- 2016 Nominee Teen Award
- Best British Group
- 2015 Nominee Teen Award
- Best British Group
- 2022 Nominee BreakTudo Award
- Best International Group (Melhor Grupo Internacional)
- 2021 Nominee BreakTudo Award
- Best International Group (Melhor Grupo Internacional)
- 2020 Nominee BreakTudo Award
- Global Artist (Artista Global)
- 2020 Nominee CelebMix Award
- Artist of the Year
- 2020 Nominee CelebMix Award
- Cybersmiler of the Year
- 2019 Winner CelebMix Award
- Best Group
- 2018 Winner Attitude Award
- Honorary Gay Award
- 2022 Nominee Global Award
- Best Group
- 2021 Winner Global Award
- Best Group
- 2020 Nominee Global Award
- Best Group
- 2019 Winner Global Award
- Best Group
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