- The youngest member of Run-D.M.C., he was born less than a month after the youngest member of the Beastie Boys, Adam Horovitz (aka "Ad-Rock"). Coincidentally, all three members of Run-D.M.C. and the Beastie Boys were born on corresponding years, with Darryl McDaniels (aka "DMC") & Adam Yauch (aka "MCA") having been born in 1964 and "Jam Master Jay" Jam Master Jay & Mike D Diamond having been born in 1965.
- Has five children. Vanessa Simmons, Angela Simmons and Joseph Simmons Jr. are from his first wife, Valerie Vaughn. Diggy Simmons Jr and Russell Simmons Jr. are from his current marriage to Justine Simmons Simmons.
- Younger brother of Russell Simmons, hip-hop record producer and Def Comedy Jam (1992) creator.
- One-third of the rap trio Run-D.M.C..
- Run-D.M.C. was voted the 48th Greatest Artists in Rock 'n' Roll by "Rolling Stone" magazine.
- Rev Run and his wife, Justine Simmons, have adopted a baby girl who they named Miley Simmons (aka Miley Justine Simmons) (2007).
- Son of Daniel Simmons.
- Brother of actor/producer Russell Simmons and Daniel J. Simmons.
- He and his wife, Justine Simmons, tragically lost their 3rd child together, due to omphalocele. Their baby girl was born 21 September 2006 and passed away shortly after her birth.
- Ex-brother-in-law of Kimora Lee Simmons.
- Has a TV show, Run's House (2005), on MTV. (September 2005)
- Granddaughter, Ava Marie Jenn, was born February 13, 2014.
- Friend of Tyrese Gibson.
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